Characterization Of Alkaloids From The Leaves Of Psychotria Malayana Jack Of Lombok Island On The Basis Of Gas Chromatography-Mass Spectroscopy

Authors : Surya Hadi; Ahmadun Azwari; Khairul Pahmi Rahmawati; Dina Asnawati; Vera Fitriya Ersalena
article cite 10 Year 2014
source: The Journal of Pure and Applied Chemistry Research
Abstract

The genus Psychotria is well known as a source of alkaloids and has contributed several novel indole-type alkaloids with quite a broad spectrum of bioactivities. This study was focused on identifying the alkaloids from the leaves of P. malayana Jack from Lombok island on the basis of Gas Chromatography-Mass Spectroscopy (GC-MS) data and the sample preparation followed acid-base extraction. The study showed that the major alkaloid contained by the leaves was hodgkinsine and other minor compounds, namely calycanthine, chimonantine, 2-ethyl-6-methylpyrazine, and 3-methyl-1,2,3,4-tetrahydro-gamma-carboline. Bioactivities of the compounds were also discussed.


Concepts :
Traditional and Medicinal Uses of Annonaceae
Alkaloids: synthesis and pharmacology
article cite 10 Year 2014 source The Journal of Pure and Applied Chemistry Research
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2014 10