ANTIBACTERIAL ACTIVITIES OF NEW AND KNOWN COMPOUNDS PREPARED FROM EUGENOL

Authors : I Made Sudarma; Sarkono; Made Ganesh Darmayanti
article cite 7 Year 2019
source: RASAYAN Journal of Chemistry
Abstract

Eugenol and its new or known derivatives were prepared through varies reactions and screened by in vitro model of antibacterial activities using pathogen bacteria: Eschericia coli, Bacillus cereus, and Staphylococcus aureus. Nearly all compounds showed antibacterial activities. The obtained results demonstrate that eugenol was still significantly more active than its derivatives, with inhibition (14-18) mm, suggesting that this chemical transformation failed to increase antibacterial activities of eugenol. The presence of nitro, cyclic sulfonic ester, N-dimethyl, quinoline, amino, isocyanate, amide and ester moieties has no ability to enhance the antibacterial activities of eugenol.


Concepts :
Essential Oils and Antimicrobial Activity
Analytical Chemistry and Chromatography
article cite 7 Year 2019 source RASAYAN Journal of Chemistry
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2019 7