Abstract
Metabolic syndrome should be considered an important issue in elderly individuals, as aging is a major contributor to the prevalence of the constellation of cardiovascular and metabolic risk factors that constitute the syndrome. However, recent studies that have investigated metabolic syndrome as a predictor of mortality in elderly shown conflicting results. The search was conducted using the PubMed, Cochrane library published in the last 20 years (January 2001 to January 2021). The search keywords were "Metabolic syndrome", "cardiovascular disease", "Mortality" and "Elderl y". Data statistical analysis using Review Manager 5.3 (RevMan Cochrane, London, UK). Based on 6 prospective cohort studies, metabolic syndrome was associated with a higher risk of cardiovascular mortality when compared to non-cardiovascular mortality in the elderly (RR = 0,68; 95% CI=0,64-0,72; P=<0,00001), there was considerable heterogeneity in all studies used (I 2 =98%; P=0,00001). Factor explaining heterogeneity between studies included sex, age, sample size, prevalence of metabolic syndrome, follow-up duration, and definition of syndrome metabolic. Cardiovascular mortality compared to those non-cardiovascular mortality, had a higher in elderly with metabolic syndrome. High blood glucose and hypertension were the main components of the cause of death from cardiovascular disease in the elderly. In addition, the combination of several symptoms of metabolic syndrome has a different risk of death and requires further research in the future.