Abstract

COVID-19 is a human-to-human infectious disease caused by SARS-CoV-2 virus and defined as a pandemic since early 2020. Because of the high spreadability and severity, it results in high rates of morbidity and mortality associated with the disease. There are several sets of signs, symptoms, or clinical parameters in an infected person, some persist for more than three weeks after the onset called Long COVID. This relates to disease severity, prolong hospital admission especially intensive care, isolation, underlying disease, and other conditions are still unknown. Long COVID is a condition of prolonged symptoms due to infection with the SARS-CoV-2 virus and may present with some neurological symptoms. These symptoms might appear as headache, anosmia, ageusia, sleep disorder, fatigue, and symptoms of neurodegeneration, neuroinflammation, and demyelination. These symptoms can further be detected by checking the nEV levels in COVID-19 patients. The management of patients with Long COVID syndrome should be pragmatic and symptomatic. Collaboration with a patient and multidisciplinary team is needed to support recovery. This review aims to evaluate the incidence and characteristics of long COVID.

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