Potential Application of Marine Algae and Their Bioactive Metabolites in Brain Disease Treatment: Pharmacognosy and Pharmacology Insights for Therapeutic Advances

Authors : Miski Aghnia Khairinisa; Irma Melyani Puspitasari; Irma Rahayu Latarissa; Nadiyah Salma Athaya; Vandie Charlie et al.
article cite 18 Year 2023
source: Brain Sciences
Abstract

Seaweeds, also known as edible marine algae, are an abundant source of phytosterols, carotenoids, and polysaccharides, among other bioactive substances. Studies conducted in the past few decades have demonstrated that substances derived from seaweed may be able to pass through the blood-brain barrier and act as neuroprotectants. According to preliminary clinical research, seaweed may also help prevent or lessen the symptoms of cerebrovascular illnesses by reducing mental fatigue, preventing endothelial damage to the vascular wall of brain vessels, and regulating internal pressure. They have the ability to control neurotransmitter levels, lessen neuroinflammation, lessen oxidative stress, and prevent the development of amyloid plaques. This review aims to understand the application potential of marine algae and their influence on brain development, highlighting the nutritional value of this "superfood" and providing current knowledge on the molecular mechanisms in the brain associated with their dietary introduction.


Concepts :
Fatty Acid Research and Health
Algal biology and biofuel production
Seaweed-derived Bioactive Compounds
article cite 18 Year 2023 source Brain Sciences
SDGs
Life below water
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2023 18