Abstract
Background: bark extract are polyphenols, which include tannins and flavonoids. Aim: ) against streptozotocin (STZ) was examined in this study. Methods: STZ (45 mg/kg BW) was administered intraperitoneally as a single dose. Twenty male rats were employed in this investigation. The rats were divided into five groups: treatment 1 (P1) was administered with STZ and provided with 100 mg/kg BW; treatment 2 (P2) was administered with STZ and provided with 200 mg/kg BW; and treatment 3 (P3) was administered with STZ and provided with 400 mg/kg BW. The negative control group (K-) was not treated with STZ and was treated with 1% Tween 80. For 14 days, the medication was administered daily. Results: The essential oil of cinnamon may lessen glomerulosclerosis, tubular necrosis, tubular degeneration, and glomerular necrosis. The kidney P3 treatment (400 mg/kg BW) produced negligible effects. Conclusion: It is possible to create cinnamon essential oil as an herbal antidiabetic medication by lowering the degree of kidney cell damage.