Potential of rutin from Rhizophora mucronata leaves as a Inhibitor of Kelch-like ECH-associated protein 1/Nuclear factor erythroid 2 related factor 2 Keap1/Nrf2): An in silico study for Alzheimer’s therapy

Authors : Legis Ocktaviana Saputri; Wiwin Azariani; Lina Permatasari; Herpan Syafii Harahap; Rohadi Muhammad Rosyidi et al.
article cite 7 Year 2025
source: Journal of Advanced Pharmaceutical Technology amp Research
Abstract

leaf extract, particularly rutin, showed promise as an AD therapeutic agent through the Keap1-Nrf2 pathway, warranting further research.


Concepts :
Alzheimer's disease research and treatments
Genomics, phytochemicals, and oxidative stress
Tryptophan and brain disorders
article cite 7 Year 2025 source Journal of Advanced Pharmaceutical Technology amp Research
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2025 7