Correlation between HDL-C levels and syntax score on coronary heart disease patients in West Nusa Tenggara General Hospital

Authors : Deasy Irawati; Romi Ermawan
article cite 0 Year 2025
source: Intisari Sains Medis
Abstract

Introduction: Coronary heart disease (CHD) is the second-highest prevalent cardiovascular disease in Indonesia. It is a complex, chronic inflammatory disease primarily caused by atherosclerosis. High-density lipoprotein cholesterol (HDL-C) level influences the development of atherosclerosis. The severity of CHD can be determined by calculating the Syntax score. Several studies have shown a significant correlation between HDL-C level and Syntax score. However, the findings were inconsistent. This study aimed to investigate the correlation between HDL-C concentration and Syntax score in CHD patients at West Nusa Tenggara General Hospital. Methods: A cross-sectional study using medical record data from CHD patients at the Regional General Hospital of West Nusa Tenggara Province from July 2018 to September 2019 was conducted. The syntax score was calculated using the Syntax Score I calculator. Pearson correlation test was used to assess the correlation between HDL-C concentration and Syntax score. The p-value <0,1 was considered significant. Results: Data from 60 patients were analyzed. In this study, 70% of the subjects had a low Syntax score, 15% had a moderate Syntax score, and 15% had a high Syntax score. Approximately 47% of the subjects had a low HDL-C concentration. No significant correlation was found between HDL-C concentration and Syntax score (p = 0.434; p > 0.1). Conclusion: There was no significant correlation between HDL-C concentration and Syntax score in CHD patients in the West Nusa Tenggara General Hospital.


Concepts :
Diabetes, Cardiovascular Risks, and Lipoproteins
Adipokines, Inflammation, and Metabolic Diseases
Cardiovascular Function and Risk Factors
article cite 0 Year 2025 source Intisari Sains Medis
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