Abstract

Thalassaemia is a severe hereditary disease, but most carriers are unaware of their risk, increasing the chance of having children with thalassaemia major. Premarital screening is important, but awareness among youths remains low. To address this, we developed and validated the Thalassaemia Education and Awareness (THALEA) Kit, a theory-based intervention for high school students using the ADDIE framework. THALEA contains nine educational materials and shows strong validity. The S-CVI/Ave was 0.95, and the average S-FVI/Ave was 0.96, indicating excellent agreement and validity across all items. In conclusion, THALEA has the potential to improve thalassaemia knowledge and screening intentions among adolescents.

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