source: Natural Product Communications
Abstract
A new, weakly antibacterial indole alkaloid, named lombine, together with the known alkaloid voacangine, have been isolated from the bark of Voacanga foetida (Bl.) Rolfe (Apocynaceae), a plant used on Lombok, Indonesia, for medicinal purposes. A combined chemo- and bio-rational strategy was developed to target this plant for investigation. Lombine was shown to be bactericidal against Staphylococcus aureus and Escherichia coli.
Concepts :
Traditional and Medicinal Uses of Annonaceae
Alkaloids: synthesis and pharmacology
Plant and Fungal Species Descriptions
article
cite 1
Year 2006
source Natural Product Communications